ipdb

One thing I have used is drop into the Python debugger (also ipdb) from within a signal handler. Then I can run a kill, and have it drop into the debugger. There are some of cute hacks to get a remote debugger which I haven't used in years. https://github.com/sassoftware/epdb can start and connect to a remote debug instance https://github.com/gotcha/ipdb

For reloading from within the repl from importlib import reload as r Then in the ipython shell you can type r(module) to reload the entire thing. So I'll often have the editor in one terminal window, and ipython in the other one, save the code and switch back the repl, and type r(t) import mymodule as t Now tie in some ipdb [1] and you have a pretty sweet setup. Also depending on your serving framework it might also have hot reloading as well, tornado, flask, etc. [1] https://github.com/gotcha/ipdb [2] https://www.tornadoweb.org/en/stable/autoreload.html https://werkzeug.palletsprojects.com/en/0.14.x/serving/

You might find this useful: https://github.com/gotcha/ipdb