Eel

I gave up a long time ago attempting to write GUIs in pure python. I've come back to them periodically to see if the landscape has changed, but I'm always disappointed. My current go-to python GUI solution is to use the Eel library. It renders GUIs in a web-browser like window with HTMl/CSS/JS.It lets you expose your python functions to JavaScript, so data can be easily transferred back and forth between the python and the JavaScript. And since it's just web-dev, it's pretty easy to make things look and feel good enough. Any other web-dev libraries like bootstrap and jquery can be used. It works pretty well for writing GUIs that put data analysis tools in front of my colleagues. https://github.com/python-eel/Eel