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soedinglab
MMseqs2
C2020–2024
soedinglab / MMseqs2

MMseqs2

MMseqs2: ultra fast and sensitive search and clustering suite

3Distinct people
3Mentions
0Explicit recommenders
2.2KGitHub stars
REPOSITORY AT A GLANCE

What to know before exploring

What it is

MMseqs2: ultra fast and sensitive search and clustering suite

GitHub

Where it is used

No documented product use has been verified yet.

What people are saying

No recommendation phrase was found in the indexed comments.

No classified warning is attached to this page. Read the discussions before treating silence as approval.

Also in these discussions

No other repository is repeatedly linked in the same discussions.

This week on Hacker News

Nov 8–Nov 15 UTC · Direct repository links and separately labeled related project stories. Indexed through 11/15/2026, 7:24:48 PM UTC.

No direct repository links were found in the indexed HN discussions over the past seven days. Older discussions are available below.

Mentions over time

HN mentions by year3 dated mentions

Observed mentions: 2020-08-04 22:54:38 UTC to 2024-11-09 19:54:05 UTC.

012020-01-01 00:00:00 UTC to 2021-01-01 00:00:00 UTC (exclusive): 1 mentions; 0 submissions, 1 comments20202021-01-01 00:00:00 UTC to 2022-01-01 00:00:00 UTC (exclusive): 0 mentions; 0 submissions, 0 comments2022-01-01 00:00:00 UTC to 2023-01-01 00:00:00 UTC (exclusive): 1 mentions; 1 submissions, 0 comments20222023-01-01 00:00:00 UTC to 2024-01-01 00:00:00 UTC (exclusive): 0 mentions; 0 submissions, 0 comments2024-01-01 00:00:00 UTC to 2025-01-01 00:00:00 UTC (exclusive): 1 mentions; 0 submissions, 1 comments2024

Counts come from the repository’s dated source evidence. Index cutoff: 2026-11-02 08:16:59 UTC.

View mention counts and date ranges
UTC ranges include their start and exclude their end. Select a period to filter the source evidence.
PeriodStart (UTC)End (exclusive, UTC)MentionsSubmissionsComments
20202020-01-01 00:00:00 UTC2021-01-01 00:00:00 UTC101
20212021-01-01 00:00:00 UTC2022-01-01 00:00:00 UTC000
20222022-01-01 00:00:00 UTC2023-01-01 00:00:00 UTC110
20232023-01-01 00:00:00 UTC2024-01-01 00:00:00 UTC000
20242024-01-01 00:00:00 UTC2025-01-01 00:00:00 UTC101

What Hacker News says

1 sources
> Not going to rewrite code I have already written, debugged and shipped. I wouldn't, either. At least unless you want a WASM/AltiVec/etc. version. But if you already have good implementations SIMDe probably won't help. OTOH, if all you have is a x86 implementation and a portable fallback, the SIMDe version of the x86 implementation will probably be faster than your portable version. That's what happened with MMseqs2 (<https://github.com/soedinglab/MMseqs2>). > Don’t forget about MXCSR register in that suite Yeah, rounding is definitely PITA. It's actually something I completely screwed up on in the beginning of the project and had to go back and correct :(. We do have some tests now which fiddle with the rounding mode to verify correctness, but could definitely use more, and obviously we can't always set a dedicated register to contro
Read the rest
l behavior, so on some platforms `_mm_getcsr`/`_mm_setcsr`/`_MM_GET_ROUNDING_MODE`/`_MM_SET_ROUNDING_MODE` becomes `fegetround`/`fesetround`, which probably won't be a problem but still makes me uncomfortable. The other area where we could really use more tests is replicating behavior for NaNs. By default we try to replicate the behavior of the function we're trying to emulate, but we currently only test NaN handling on a few functions :(. If you use -ffast-math or -ffinite-math-only we disable that code (compilers define __FINITE_MATH_ONLY__), though, and just use the fastest implementation we can.
In SIMD Everywhere: 0.5.0

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